Body systems and how they connectInvestigateabout 40 min
Predict it, then test it
Reaction time, a real enzyme test, exercise data and a fever that is not a malfunction
Turn the claims from earlier layers into experiments you can actually run: a ruler-drop reaction test, an iodine test for digested starch, pulse and breathing data before and after exercise, and a look at why a fever is a controlled response rather than a failure.
In this part you’ll
- Explain why muscles work in opposing pairs, and find the one hand-over that carries force rather than a substance.
- Use a falling ruler and the physics of free fall to measure and calculate a real reaction time.
- Design and explain a fair test with a control, using the amylase-and-iodine experiment as the model.
- Compare how much pulse and breathing rate rise with exercise, using real data.
- Explain fever as a deliberately raised set point, not a broken control system.
Discover introduced the seven systems. Understand explained how each hand-over works. This layer asks you to stop taking the book's word for it: predict what will happen, then actually test it.
Real science works this way. You state, in advance, what you expect — out loud or on paper, so you cannot quietly move the goalposts afterwards. Then you run the test. Sometimes you are right, and that is satisfying. Sometimes you are wrong, and that is more useful, because now you know precisely where your idea broke.
Every experiment below uses only things found in an ordinary classroom or home: a ruler, a stopwatch, a mirror, your own pulse, a spoonful of cooked rice. None of it requires a laboratory, and none of it is dangerous if you follow the few safety notes.
Chapter 01
Muscles: the last hand-over before movement
You met the nerve-to-muscle hand-over in Understand: a nerve ending releases a chemical, the muscle fibre receives it, and the fibre contracts. Here is what "contracts" is actually built from.
Inside a muscle fibre are two kinds of protein filament, laid out in overlapping rows. When the chemical signal arrives, calcium is released inside the fibre, and that calcium is the trigger that lets the two kinds of filament grip each other and slide past one another, like two combs pushed together. Thousands of fibres doing this at once is what you feel as the whole muscle shortening.
Notice what is not happening: no single filament gets shorter. The filaments themselves stay the same length. The shortening is entirely down to how far they slide over each other — a small slide, repeated across thousands of fibres, adds up to a muscle that can shorten by a third of its length in a fraction of a second.
Lab
Follow one contraction from the nerve signal arriving to the bone actually swinging, and find the one hand-over that carries force instead of a substance.
Muscular system
Moving: pullwith the skeletal systemMuscles pull on bones to move you — and they can only pull, never push.
Skeletal system (the system it hands over to)
- Bones⇅ hand-over
- Joints
- Bone marrow
- Protection
Step 1 of 7
Order arrives · motor end plate
The chemical signal from the motor nerve reaches the muscle fibre at the nerve-muscle junction.
Where the two systems meet
⇅ Tendon ↔ bone
at the tendon, where muscle grips bone — Muscles cannot push. They pull, and the tendon passes that pull to a bone, which swings at a joint like a lever.
Think you have it? Try a few questions about the route.
Text version of this activity
Seven steps from a nerve signal to a moving limb, with the skeletal system drawn alongside.
The signal arrives at the junction, calcium floods the fibre, and two kinds of filament slide past each other — the whole mechanism of a contraction, repeated in thousands of fibres at once. The muscle shortens and pulls on its tendon.
The hand-over is the last step: the tendon transfers that pull to the bone at a joint. Every other hand-over in this topic carries a substance — oxygen, glucose, a chemical signal. This is the one that carries force, and it only goes one way: muscles pull bones, never the reverse.
The final step is a reminder that a muscle can only pull. To reverse the movement, a second muscle on the other side of the joint must contract instead. Turn the quiz on and it asks which step would fail if the calcium release did not happen (the fibre would receive the signal but never contract).
Predict first
Related to
Anatomy of the human bodyThe names and exact locations of the biceps, triceps, calf and shin muscles you just felt are set out properly in the anatomy topic.
Try it
Chapter 02
How fast is a decision, really?
A reflex is decided in the spinal cord in about 20 ms. A voluntary reaction — seeing something and choosing to respond — takes roughly 200 ms, ten times longer, because it goes all the way to the brain and back. Can you actually measure that second number yourself, with nothing but a ruler?
You can. It uses the one piece of physics every falling object obeys: it speeds up at a fixed rate, about 9.8 metres per second every second, whatever it weighs. If you know how far something fell, you can work out how long it fell for — even if the "something" is a ruler and the "how long" is your own reaction time.
Lab
Try the ruler-drop reaction test yourself, then plot a class's results and read off the mean, median and range.
Ruler-drop test, one class of 12 (distance caught, cm) (cm)
Challenge 1What is the mean catching distance for the class? (Answer: 19.5 cm.)
Target: mean = 19.5. Right now the mean is 19.5. Add or remove dots below — it checks as you go.
Tap the number line to add a value; tap a dot to remove it. Dashed long line = mean (●), dotted line = median (▲).
The values (12)
- 15
- 18
- 22
- 25
- 14
- 20
- 17
- 23
- 19
- 21
- 16
- 24
sum ÷ count = 234 ÷ 12 = 19.5
141516171819202122232425
12 values (even), so take the two middle ones: (19 + 20) ÷ 2 = 19.5.
Every value appears only once. The usual convention: when nothing repeats, we say there is no mode.
max − min = 25 − 14 = 11
Text version of this activity
The test. One person holds a ruler vertically, zero end down, between a partner's open thumb and finger without touching it. Without warning, they let go. The partner catches it as fast as they can, and you read off how many centimetres slipped through before it was caught.
The data. A sample class of twelve got: 15, 18, 22, 25, 14, 20, 17, 23, 19, 21, 16, 24 cm. Mean 19.5 cm, range 11 cm.
Drag the dots to enter your own class's results and the mean, median, mode and range recompute live. The challenges ask you to find each measure and to say, in your own words, what a big range would mean about a group of people (that reaction times vary a lot between individuals, and even for the same person from one try to the next).
Worked example
0 / 6 steps shownTurning a falling distance into a reaction time
The sample class's mean catching distance was 19.5 cm. A falling object drops a distance d in time t according to d = ½ × g × t², where g ≈ 9.8 m/s². How long, in milliseconds, did it take the class on average to react?
Predict first
Used in
GravityThe ruler-drop test only works because every falling object speeds up at the same fixed rate regardless of its mass — the free-fall rule explored fully in the gravity topic.
Chapter 03
Watching an enzyme actually work
Understand told you that saliva contains amylase, an enzyme that starts cutting starch into sugar. That is a claim you can test directly, using a simple colour change that is one of the oldest tricks in a school laboratory.
Iodine solution turns blue-black in the presence of starch, and stays its normal brown-orange colour if no starch is left. So the test is: take two samples of the same starchy food, treat one with saliva and one without, wait, then add iodine to both and compare.
The amylase test, step by step
- Step 01Preparetwo samples
Take two small, equal spoonfuls of cooled, cooked rice or a starch-and-water paste, in two separate cups.
- Step 02Add salivato cup A only
Add a little saliva (your own, on a clean spoon) to cup A and stir. Leave cup B untouched as the control.
- Step 03Wait≈ 5 minutes
At room or body warmth, amylase needs a few minutes to do noticeable work — the same warmth your mouth stays at.
- Step 04Add iodinea drop in each
Add one drop of iodine solution to each cup, and look at the colour without stirring it in.
- Step 05Comparethe result
Cup B (no saliva) should turn dark blue-black — starch is still there. Cup A (with saliva) should stay closer to its original colour, or turn a much paler blue — much of the starch has already been cut into sugar.
Predict first
Lab
Guess true, false or "it depends" for eight common claims about the body, then read the reasoning behind each.
Before you sort, guess for yourself: true, false, or "it depends"? Then read why.
8 cards, 3 bins. Tap a card, then tap its bin. You can also drag, or press a bin’s number key.
Text version of this activity
Eight commonly heard claims, three bins: True, False, It depends.
Most of the classic ones here are false: chewing gum does not speed digestion, cracking knuckles is not linked to arthritis, dim light does not permanently damage eyes, wet hair does not cause colds (viruses do), a sneeze does not stop your heart, and growing pains are not bone damage.
Two are genuinely true and both connect straight back to earlier layers: chewing more thoroughly really does help digestion (more surface for enzymes), and exercising hard on a full stomach really can feel unpleasant (blood is being asked to go to muscles and gut at the same time).
The point of the game is not memorising eight facts. It is noticing that a claim sounding plausible, or being widely repeated, is not evidence — the same lesson Understand taught with the tennis-court lung and the 10-to-1 bacteria ratio.
Chapter 04
What running does to your breathing — measured
Discover measured pulse before and after exercise. Do the same for breathing rate, and a genuine question appears: does breathing speed up by a bigger factor than the pulse does, or a smaller one? Predict first, then look at the numbers.
Predict first
Lab
Plot a class's breathing rate before and after exercise, and compare how much it rises with how much the pulse rises.
Challenge 1Find the mean resting breathing rate. (Answer: 20.5 breaths/min.)
Target: mean = 20.5. Right now the mean is 20.5. Add or remove dots below — it checks as you go.
Tap the number line to add a value; tap a dot to remove it. Dashed long line = mean (●), dotted line = median (▲).
The values (12)
- 18
- 20
- 22
- 17
- 24
- 20
- 19
- 21
- 22
- 18
- 25
- 20
sum ÷ count = 246 ÷ 12 = 20.5
171818192020202122222425
12 values (even), so take the two middle ones: (20 + 20) ÷ 2 = 20.
20 appears 3 times — more than any other value.
max − min = 25 − 17 = 8
Text version of this activity
Two dot plots, editable, of the same twelve children's breathing rate: 18, 20, 22, 17, 24, 20, 19, 21, 22, 18, 25, 20 breaths a minute at rest, rising to 34, 38, 42, 32, 46, 38, 36, 40, 41, 33, 48, 37 straight after one minute of star jumps.
Mean rises from 20.5 to 38.8, a factor of 1.89. Set this beside the pulse data from Discover, where the mean rose by a factor of 1.74. The two are close, and both are driven by the same rising-carbon-dioxide alarm — the heart and the lungs are not two separate decisions, they are one decision acted out by two systems at once.
The challenges ask for the mean, median and a comparison between the two datasets' spread — is the class more alike or less alike once everyone is out of breath?
Used in
Data handlingComparing how much two measurements rise by, as a factor rather than a raw difference, is exactly the kind of reasoning data handling gives you the tools for.
Chapter 05
Fever: a controlled response, not a malfunction
Everything in Understand's homeostasis chapter described the body defending a fixed target, 37.0 °C. A fever looks, at first, like that system failing — temperature climbing when it is supposed to stay put. It is the opposite. In a fever, the body's control centre deliberately raises its own target, usually because chemicals released by the immune system tell it to.
Many germs grow best at the body's normal temperature and struggle a little above it. Raising the target a degree or two makes the whole body a slightly worse home for them, while your own cells cope with the change easily. A fever, within reason, is your immune system turning up the thermostat on purpose.
Predict first
Explore
Guess the size, then check
Pick an organ and see how close your guess was.
- Guess a size
- Compare to your fist
- About right
- Roughly 300 g
- Beats on, unpaused
About one fist
Roughly the size of its owner's own clenched fist, and about the same in a small child as the child's own small fist — the heart grows along with the rest of the body. Most people guess bigger.
Chapter 06
Same design, different people
Every number in this topic — resting pulse, breathing rate, reaction time, sleep needed — has been given as a typical range, not a single fixed value, and that was deliberate. Real bodies vary, healthily, for reasons that include age, fitness, body size, genetics and simply being a different person.
This is worth investigating directly rather than assuming. Two people of the same age can have resting pulses ten or twenty beats apart and both be perfectly healthy. A fair test compares a person with themselves — before and after exercise, or one week and the next — far more reliably than it compares one person with another.
Lab
Connect eight simple experiments from this topic with the thing each one actually demonstrates.
Match each experiment to what it actually measures or shows.
8 pairs are hiding in two mixed-up columns. Pick one from each side to join them.
Text version of this activity
Eight everyday tests, matched to what each one is really evidence for.
- Ruler-drop ↔ voluntary reaction time (via the physics of falling).
- Tendon-hammer tap ↔ a spinal reflex, far faster than a voluntary reaction.
- Iodine on rice plus saliva ↔ whether starch has already been cut into sugar.
- Pulse before/after exercise ↔ how much harder the heart works under load.
- Breathing count before/after exercise ↔ the matching rise in breathing.
- Chewing roti slowly ↔ amylase working, noticed as sweetness.
- Feeling your calf while walking ↔ the "second heart" effect of muscles squeezing veins.
- Timed breath-holding ↔ carbon dioxide, not a shortage of oxygen, driving the urge to breathe.
None of these need special equipment. That is the point of an Investigate layer: the claims in this topic are not mysterious facts to accept, they are things you can go and check.
Chapter 07
How fast do you recover? A second measurement
Discover's "find your pulse" activity asked you to keep counting once a minute until you were back to your starting rate, and to write down how long that took. That single number — recovery time — turns out to be one of the more informative measurements in this whole topic, and it is not the same as your resting pulse or your peak pulse.
Two people can reach the exact same peak pulse after the exact same effort, and still recover at very different speeds. The one who calms back down faster is, on this particular measure, fitter — regardless of what their resting pulse was to start with.
| Minutes after stopping | Fitter person (bpm) | Less fit person (bpm) |
|---|---|---|
| 0 | 134 | 134 |
| 1 | 118 | 126 |
| 2 | 104 | 119 |
| 3 | 96 | 113 |
| 4 | 90 | 108 |
| 5 | 84 | 103 |
| 6 | 79 | 99 |
Worked example
0 / 5 steps shownComparing two recovery curves
Both people reach the same peak, 134 bpm, after the same hard effort. In the first minute afterwards, the fitter person's pulse drops to 118 bpm and the less fit person's drops to 126 bpm. Compare how much each pulse actually fell.
Try it
Predict first
Chapter 08
Does food need gravity to go down?
Discover's steps described peristalsis — a wave of muscle squeezing behind the food and relaxing in front of it — as working "even upside down". That is a specific, testable claim, and you do not need to actually hang upside down to test a safe version of it.
Predict first
Try it
Chapter 09
How fast does colour come back?
Here is a test that needs no equipment at all beyond your own fingernail and a way to count seconds. Press firmly on a fingernail until the flesh underneath turns pale — you have just squeezed the blood out of the capillaries there. Let go, and time how long it takes the pink colour to return.
This is called capillary refill, and it is a genuinely quick, real signal of how well blood is being delivered to your extremities, used in exactly this simple form by doctors and first-aiders as a rough, immediate check.
Lab
Test your own capillary refill time, then plot a class's results and compare with a commonly used rough guideline.
Capillary refill time, one class of 12 (seconds) (s)
Challenge 1Find the mean refill time for the class. (Answer: 1.83 s.)
Target: mean = 1.83. Right now the mean is 1.83. Add or remove dots below — it checks as you go.
Tap the number line to add a value; tap a dot to remove it. Dashed long line = mean (●), dotted line = median (▲).
The values (12)
- 1
- 2
- 2
- 1
- 3
- 2
- 1
- 2
- 3
- 1
- 2
- 2
sum ÷ count = 22 ÷ 12 ≈ 1.83
111122222233
12 values (even), so take the two middle ones: (2 + 2) ÷ 2 = 2.
2 appears 6 times — more than any other value.
max − min = 3 − 1 = 2
Text version of this activity
The test. Press a fingernail firmly for a few seconds until it turns pale, release, and count how many seconds it takes to return to its normal pink colour.
Sample data. A class of twelve got: 1, 2, 2, 1, 3, 2, 1, 2, 3, 1, 2, 2 seconds. Mean 1.83 s, range 2 s — all comfortably inside the commonly used rough guideline of well under 2 seconds for a warm, healthy hand.
This is one more small, safe measurement you can genuinely repeat: cold hands, a hand held above the head versus hanging down, or straight after exercise are all interesting, harmless variations to test and compare against your own resting value.
Chapter 10
Design your own test
This layer has walked you through five ready-made experiments. The last and best test of whether you have understood the idea of a fair test is designing one yourself, from scratch, for a claim nobody has checked for you yet.
A checklist for designing a fair test
- Step 011. State the claimclearly
Write the claim as a single sentence you could imagine being wrong. "Chewing gum speeds digestion" is testable; "digestion is complicated" is not.
- Step 022. Decide what to measurea number or a clear yes/no
Pick something you can actually observe or count, like the ruler-drop distance or the iodine colour, not a vague feeling.
- Step 033. Change exactly one thingthe variable
Everything else — the food, the amount, the timing, the person — should be kept as similar as possible between your test and your control.
- Step 044. Keep a controlthe "nothing changed" case
Without one, you cannot tell whether your result came from the thing you changed or from something else entirely.
- Step 055. Predict firstbefore you look
Write down what you expect to happen, so the result can genuinely surprise you.
- Step 066. Run it, and be honestabout the result
Report what actually happened, even if it does not match your prediction — that mismatch is often the most useful part.
Reflect
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Words to know
All maths vocabulary →Words for this layer
- Control (in an experiment)
- The sample or condition left unchanged, so you can tell what "no effect" looks like.
- Example: Cup B, with no saliva added, in the amylase test.
- Fair test
- Changing exactly one thing at a time while keeping everything else the same.
- Example: Same rice, same amount of iodine — the only difference is saliva or not.
- Mean, median, mode, range
- Four different summaries of a set of measurements: the average, the middle value, the most common value, and the spread from lowest to highest.
- Example: A pulse data set with mean 77.3 bpm and range 20 bpm.
- Set point
- The value a control system is currently trying to hold — usually fixed, but reset upward on purpose during a fever.
- Example: Body temperature's normal set point is about 37 °C.
- Opposing pair
- Two muscles arranged so one bends a joint and the other straightens it, because a muscle can only pull.
- Example: Biceps and triceps.
Quick check
Check yourself: predicting and testing
9 questions · answer what you can, then check. Getting one wrong is useful.
Reflect
This stays on this page only. It isn’t saved or sent anywhere.
Keep this
Cheat sheet
- Muscles only pull. Movement both ways needs opposing pairs (biceps/triceps); the muscle-to-bone hand-over carries force, not a substance.
- Reaction time, measured with a falling ruler: distance fallen gives time via d = ½gt². A class mean of about 19.5 cm corresponds to roughly 199 ms — close to the 200 ms used elsewhere in this topic.
- A reflex (≈20 ms) falls too little to measure with a ruler — that is a real limit of the method, not a failure of the idea.
- A fair test changes one thing and keeps a control — cup B with no saliva is what makes cup A meaningful.
- Chewing more thoroughly genuinely helps digestion; most other "common knowledge" claims tested in this layer (gum, knuckle-cracking, wet hair, dim light) do not hold up.
- Exercise roughly doubles both pulse and breathing — factors of about 1.74 and 1.89 in the sample data — from the same carbon-dioxide trigger.
- Fever is a reset target, not a broken thermostat. Chills at the start happen because the target jumped before the body caught up.
- Averages describe groups, not individuals — a wide range is normal, and comparing yourself with yourself over time is more meaningful than comparing with a class average.
- Recovery time is its own fitness signal, separate from resting or peak pulse: in the sample data the fitter person's pulse fell 2 times as fast in the first minute after stopping.
- Peristalsis works in any orientation — it is a muscular squeeze, not a gravity-assisted fall, which is why swallowing works lying down or in orbit.
- Capillary refill — how fast colour returns after a fingernail is pressed pale — is a real, simple circulatory check; a class average around 1.83 s is typical.
- A well-designed test states one testable claim, changes exactly one variable, keeps a control, and predicts before looking at the result.
Where this comes from
Sources
Human cardiovascular system (opens another website) — Encyclopaedia Britannicaawaiting check
Supports the heart as a double pump with four chambers and valves, the pulmonary and systemic circuits, arteries, veins and capillaries, roughly 5 litres of blood and a resting output near 5 litres a minute, blood pressure, and the composition of blood with haemoglobin carrying oxygen.
Human respiratory system (opens another website) — Encyclopaedia Britannicaawaiting check
Supports the air path from nose to alveoli, warming and filtering of air in the nose, the diaphragm and rib muscles doing the work of breathing, a tidal volume of about 500 mL, resting breathing rates, and the composition of inhaled versus exhaled air (about 21%/16% oxygen, 0.04%/4% carbon dioxide).
Human nervous system (opens another website) — Encyclopaedia Britannicaawaiting check
Supports the brain, spinal cord and peripheral nerves, sensory and motor neurons, conduction speeds from about 1 to 120 metres per second depending on fibre thickness and myelin, the reflex arc passing through the spinal cord without waiting for the brain, and voluntary versus involuntary control.
Homeostasis (opens another website) — Wikipediaawaiting check
Supports negative feedback control of core temperature near 37 °C, sweating and shivering, thirst and water balance, blood glucose control by insulin and glucagon as slow chemical (endocrine) messages, and fever as a deliberately raised set point rather than a failure of control.
Human digestive system (opens another website) — Encyclopaedia Britannicaawaiting check
Supports the order of the digestive tract, chewing and saliva, salivary amylase as the first enzyme, peristalsis, stomach acid and pepsin, the roles of liver, gall bladder and pancreas, absorption at the villi, water recovery in the large intestine, and transit times of roughly one to three days.
End of Investigate
What you just read
- Explain why muscles work in opposing pairs, and find the one hand-over that carries force rather than a substance.
- Use a falling ruler and the physics of free fall to measure and calculate a real reaction time.
- Design and explain a fair test with a control, using the amylase-and-iodine experiment as the model.
- Compare how much pulse and breathing rate rise with exercise, using real data.
- Explain fever as a deliberately raised set point, not a broken control system.
- Next depthGo deeper: Go deeperMechanisms, reasoning, calculations and nuance.
- Practise79 questionsHints and a worked solution for every question — or play a 10-question round.
- Step backUnderstandGo back over the ground before this one — you can move up and down as often as you like.
- TopicAll of body systems and how they connectThe whole ladder, the connections and the words to know, on one page.
The web
Explore a connection
Builds on
Anatomy of the human bodyOnce you know where each organ sits, you can follow how they pass work to each other.
Related toanother area
GravityBones, muscles and blood pressure are all built for a life spent pulling against Earth's gravity — which is why astronauts weaken in orbit.
Used inanother area
Data handlingPulse and breathing rate before and after exercise are real class data to average, compare and graph.
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Revision 1 · release preview-7e1cbbcc4f · accepted 20/09/2026